TauroPace™
TauroPace™ is an antimicrobial solution designed to keep CIEDs sterile before implantation.
Indication and effect
TauroPace™ is certified for use during the procedure of placing or revising CIEDs with the aim to upgrade, downgrade, or substitute (i.e. during any surgical procedure). This includes (but is not limited to) the following CIEDs:
- pacemakers (PM)
- implantable cardioverter defibrillators (ICD)
- PMs and ICDs able to deliver cardiac resynchronisation therapy (CRT-P, CRT-D)
- cardiac contractility modulation (CCM)
- subcutaneous ICD (S-ICD)
- leadless PMs
- implantable or injectable loop recorders or monitors (ILR/ILM)
- all respective hardware (generator, leads, torque wrench, dilators, sheaths, wires, etc.)
TauroPace™ is designed to protect CIEDs:
- It prevents bacterial and fungal adhesion to CIED hardware.
- It is antimicrobially active against pathogens, with no resistance patterns having been observed.
Composition
The main ancillary active ingredient of TauroPace™ is taurolidine. Taurolidine has a broad antimicrobial activity against relevant pathogens, including (but not limited to) multi-resistant superbugs (e.g. MRSA, MRSE, Klebsiella, Candida species).
Application
TauroPace™ is applied by wiping soaked swabs during the surgical procedure before implantation.
Expert recommendations
TauroPace™ is available in a majority of EMEA countries. With increasing use, the solution has become a standard of care in many implanting centres.
TauroPace™ is recommended for application to CIED in all implantation procedures.
Contraindications
To date, there are no known adverse effects of TauroPace™ during and after implantation procedure. There are no contraindications known other than pre-existing allergies against taurolidine or polyvinylpyrrolidone (PVP) – either not reported to date.
Safety
If you consider using TauroPace™, please do not place any other liquid on the CIED.
Package sizes
Tauropace™ is available in 100 ml vials. One vial should be used per patient/procedure.
Storage & transport
TauroPace™ must be stored at temperatures between 15 °C and 25 °C. Please note that freezing TauroPace™ will eventually destroy the solution and interfere with its antimicrobial activity.