Prevention of contamination

TauroPace™

A safe solution for CIEDs

Cardiac implantable electronic devices (CIED) – e.g. pacemakers or implantable cardioverter defibrillators – can be life-saving for patients with arrhythmic heart conditions.

TauroPace™ is an antimicrobial solution used during CIED surgery before final placement – i.e. surgical procedures of implantation, lead implantation, or extraction, with the aim of up- or downgrading, revision, or generator substitution. Its main ancillary active ingredient is taurolidine, a substance commonly used for lock solutionsin central-venous access devices.  

Antibiofilm efficacy

  • Prevention of bacterial and fungal adhesion to the foreign body and body tissues
  • Direct disruption of bacterial and fungal cell walls
  • Neutralisation of released endo- and exotoxins

Antimicrobial efficacy

  • Strong activity against MRSA and VRSA (no known gaps)
  • Gram-positive activity – including oxacillin and methicillin resistant S. aureus, coagulase (-) staphylococci (CoNS), and vancomycin-resistant enterococci (VRE)
  • Gram-negative activity – including Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and fungi

 

TauroPace™ is not an antibiotic compound. No adverse events or resistance patterns have been observed.


No tissue or organ toxicity

  • TauroPace™ is a certified medical device. You can apply it without adjusting standard surgical techniques during implant, replacement, or revision procedures.
  • The solution does not provide nidi for pathogens to multiply.
  • Adjunct use of TauroPace™ during any CIED procedure can effectively prevent CIED contamination.

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